RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
WNT3A
RNA ID
RNA Type
mRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
Immunohistochemistry; qRT-PCR etc.
Target
NA
Pathway
WNT/B-CATENIN signaling pathway
PubMed ID
Title
Functional Wnt signaling is increased in idiopathic pulmonary fibrosis
Year
2008
Function
"In IPF lung specimens, Wnt1, 7b, and 10b mRNA levels were markedly upregulated (log-fold change of 1.19+-0.43, 1.05+-0.43, And 1.58+-0.59, Respectively), whereas Wnt3a was significantly downregulated (log-fold change 1.93+-0.65)."